Running
310. The Fatigue Resistance Episode! Rachel Entrekin Makes History at Cocodona, Women v. Men Durability, Fueling and the Central Nervous System, Brain Changes, and More
Some Work, All Play›
May 12, 20261:34:02
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We had some HYPOTHESES for this amazing episode! The main topics all revolved around fatigue resistance (often called “durability” in the literature), which we think is the most exciting area of training theory and physiology. It started with Rachel Entrekin’s legendary overall win at the Cocodona 250, an event that explores some of the strangest and coolest parts of endurance.
Our big theory: what we’re seeing in these wild ultras is directly connected to what we see in short distances. A new study looked at fatigue resistance variations between men and women, with some shocking results. We expand the scope to talk about the literature generally before going to some ideas for how it all might relate to the central nervous system.
...And how it relates to fueling. You could probably guess that we were going to talk about carbs.
Plus, we answer questions about the culture of fueling for young athletes and feeling good after long runs!
This one starts with a description of Megan’s health journey. The hottest vacation is apparently a 3-day stay in Boulder Community Hospital. Things are scary, but we’re holding onto hope for the future.
We love you all! HUZZAH!
-David and Megan
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"310. The Fatigue Resistance Episode! Rachel Entrekin Makes History at Cocodona, Women v. Men Durability, Fueling and the Central Nervous System, Brain Changes, and More" is an episode of Some Work, All Play. Runtime 1 hr 34 min. Published May 12, 2026. Hit play above to stream it here, or open the free Spot Sports app for background play and offline downloads.
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Quick FAQ
- When was this episode published?
- May 12, 2026.
- How long is this episode?
- 1 hr 34 min.
- What podcast is this from?
- Some Work, All Play. Browse the full back catalog on the show page.
- What does this episode cover?
- Some Work, All Play covers running. This episode runs on the show's regular cadence.
