Week 10 is here and CFP hopes and dreams are on the line. Will Arch Manning be back to help lead the Longhorns to a much needed Top-10 win over Vanderbilt, will leaving the state of Florida for the first time all season hurt Miami’s chances at SMU and can USC prove they are still a CFP contender by beating Nebraska in Lincoln? Plus, will Florida play loose and aggressive in their first game without Billy Napier against a hungry Georgia team and whose playoff dreams will come crashing down in Knoxville on Saturday night: Oklahoma or Tennessee? Greg McElroy delivers his in-depth previews and predictions for the biggest games of the weekend. 0:00 Intros 2:10 Penn State at Ohio State preview and prediction 8:55 Vanderbilt at Texas preview  19:50 Miami at SMU preview and prediction  26:30 Georgia at Florida preview and prediction 33:35 Texas Tech at Kansas State preview and prediction 39:40 Oklahoma at Tennessee preview and prediction 46:00 USC at Nebraska preview and prediction 53:10 Cincinnati at Utah preview and prediction 58:36 Week 10 quick hitters 1:01:08 Giant Killers ✔️Subscribe to ESPN+ http://espnplus.com/youtube ✔️ Get the ESPN App: http://www.espn.com/espn/apps/espn ✔️Subscribe to ESPN on YouTube: http://es.pn/SUBSCRIBEtoYOUTUBE ✔️ Subscribe to NBA on ESPN on YouTube: http://bit.ly/SUBSCRIBEtoNBAonESPN ✔️ Watch ESPN on YouTube TV: http://es.pn/YouTubeTV