Mike Florio and Chris Simms preview a fantastic game between the Rams and 49ers, debating if Sean McVay can get some revenge against Kyle Shanahan and explaining why Los Angeles will beat San Francisco in a close one. #NBCSports #NFL #ChrisSimmsUnbuttoned » Watch Live Sports on Peacock: https://peacocktv.smart.link/v82e9dl56 » Subscribe to NFL on NBC: https://www.youtube.com/NFLonNBC?sub_confirmation=1 NBC Sports Group serves sports fans 24/7 with premier live events, insightful studio shows, and compelling original programming. NBC Sports is an established leader in the sports media landscape with an unparalleled collection of sports properties that include the Olympics, NFL, Premier League, Big Ten, NASCAR, PGA TOUR, the Kentucky Derby, Tour de France and many more. Subscribe to our channel for the latest sporting news and highlights! 'Chris Simms Unbuttoned' features in-depth Xs and Os NFL analysis; one-on-one interviews with players, coaches, executives, and draft prospects; game recaps and previews; gambling segments; extensive player analysis leading into the NFL draft; and much more. Watch more from NBC Sports on YouTube: https://www.youtube.com/nbcsports Visit NBC Sports: https://www.nbcsports.com Find NBC Sports on Facebook: https://www.facebook.com/NBCSports Follow NBC Sports on Twitter: https://twitter.com/nbcsports Follow NBC Sports on Instagram: https://www.instagram.com/nbcsports/ https://www.nbcsports.com/nfl/sunday-night-football https://nbcsports.com/motors/nascar https://nbcsports.com/soccer/premier-league NFL Week 10 preview: Los Angeles Rams vs. San Francisco 49ers | Chris Simms Unbuttoned | NFL on NBC https://www.youtube.com/NFLonNBC