Check out highlights from Week 2 of the 2025 college football season as the Louisville Cardinals beat the James Madison Dukes, 28-14. Isaac Brown had for 104 YDS, including a game-sealing 78-yard touchdown late in the fourth quarter for Louisville. ✔️Subscribe to ESPN+ http://espnplus.com/youtube ✔️ Get the ESPN App: http://www.espn.com/espn/apps/espn ✔️Subscribe to ESPN on YouTube: http://es.pn/SUBSCRIBEtoYOUTUBE ✔️ Subscribe to NBA on ESPN on YouTube: http://bit.ly/SUBSCRIBEtoNBAonESPN ✔️ Watch ESPN on YouTube TV: http://es.pn/YouTubeTV