The Matchups That Will Decide 49ers Broncos

49ers vs. Broncos is a classic strength-on-strength matchup — and this game could come down to which team can force the other out of its comfort zone.

In this preview, we break down the biggest matchups San Francisco has to solve on both sides of the ball. How should Kyle Shanahan attack Denver’s defense? What can the 49ers do to create favorable looks for Brock Purdy and Christian McCaffrey? And on defense, what does San Francisco need to take away from Sean Payton and the Broncos offense?

We’ll look at the schemes, personnel matchups, pressure points, and tactical advantages that could decide the game.

If you’re a 49ers fan who doesn’t spend all week studying Denver, this is everything you need to know before kickoff.

Topics include:
- 49ers vs. Broncos preview
- Kyle Shanahan vs. Sean Payton
- How the 49ers can attack the Broncos defense
- Brock Purdy and the 49ers offense
- Christian McCaffrey matchup advantages
- How San Francisco should defend Denver
- Key matchups that could decide the game
- 49ers offensive and defensive strategy
- San Francisco 49ers news and analysis

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