At home in Clemson, the Tigers went on the road on Friday night and defeated the #20 Cardinals, 20-19. Louisville had chances to take the lead in the fourth quarter, but they missed two long field goal attempts in the last 4:30 of the game. Clemson running back Adam Randall ran the ball 15 times for 105 yards and two touchdowns. Cade Klubnik passed for 187 yards on 22 of 34 passing. Louisville running back Keyjuan Brown ran for 135 yards on 15 attempts. Quarterback Miller Moss completed 19 of 27 passes for 212 yards.