At home in Louisville, the Cardinals defended their home court and defeated the Mustangs, 91-54. SMU shot 43.8% from the field, and Louisville shot 48.6%, but the Cardinals turned the Mustangs over 24 times. Tajianna Roberts led a balanced Louisville scoring attack with 15 points. Imari Berry had 11 points, nine rebounds, and three assists. Elif Istanbulluoglu added 11 points, four rebounds, adn tow assists. SMU's Paulina Paris scored a game-high 20 points, making 4-7 three-pointers.