Pat Mayo, Tyler Tamboline and John Breslin of 4for4 DFS Fantasy break down the best 2025 NFL Week 10 DraftKings picks, lineups, and DFS strategy to help you build winning rosters. We cover ownership projections, game stacks, top plays, fades, and Underdog Pick’em picks for Week 10. Whether you’re entering GPPs or cash games, this guide has you covered.

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Show Index

00:00 Intro

4:07 Optimal/MIN Stack

27:12 NE/TB

37:06 BAL Stack

51:49 SEA/ARZ

underdog pick’em

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