Is Sunday The Biggest Game of the Mahomes - Reid Era?

The Chiefs are already down two games in the loss column to the Broncos and would appear to have no path to a Division Championship without winning this game. So do they get it?

Jeff Chadiha (NFL Network/NFL.com/@JeffriChadiha), Sam McDowell (Kansas City Star/KCStar.com/@SamMcDowell11) and Soren Petro (Sports Radio 810 - WHB/810whb.com/@SorenPetro) discuss the injuries, the matchups and more!

- Biggest regular season game of the Mahomes - Reid era?
- Should Josh Simmons play in this game?
- What to make of Reid’s 22-4 record after the Bye?
- Can the Chiefs OL handle the Bronco pass rush?
- How do the Chiefs take advantage of no Patrick Surtain?
- Does Xavier Worthy have to be big in this game?
- Can the Chiefs Defense expose the Broncos weaknesses?
- Keys to the Game!
- Predictions!