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The Denver Broncos enter their Week 4 matchup against the San Francisco 49ers with a massive injury advantage, as Jaylen Waddle and Marvin Mims Jr. are ready to play while San Francisco deals with several key injuries. We break down the latest Broncos injury report, Talanoa Hufanga’s return to San Francisco, Denver’s Super Bowl hosting bid, and Sean Payton’s hilarious ManningCast joke. Plus, Bo Nix is closing in on NFL history, the Broncos’ pass rush faces a major challenge against Brock Purdy, and Denver looks to extend its 10-game winning streak against NFC opponents. Can the Broncos take advantage of a depleted 49ers roster and move to 3-1? Zac Stevens goes inside Broncos practice for the latest updates & news for Broncos Country.
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"Broncos's MASSIVE Injury Advantage, Sean Payton JOKES About Manning Cast, Super Bowl Bid & More" is an episode of DNVR Denver Broncos Podcast. Runtime 7 min. Published October 2, 2026. Hit play above to stream it here, or open the free Spot Sports app for background play and offline downloads.